18. University of Gothenburg (UGOT)
Partner Leader : Jonas Tegenfeldt
Weblink : http://nanobio.ftf.lth.se/~tegen
Tasks in the project include :
DNA molecules confined in nanoscale channels assume an elongated conformation. With appropriate choice of dyes, this allows us to directly visualize the entire DNA molecule and precisely localize specific probes along the DNA, thereby accessing sequence-related information on the single-molecule level. Standard epifluorescence techniques will be used together with more advanced single-molecule detection schemes as well as high-precision localization of bound labels along DNA. Nanoscale devices will be made using standard UV-lithography and electron-beam lithography.