Publications 2010

  1. Gauging the Flexibility of Fluorescent Markers for the Interpretation of Fluorescence Resonance Energy Transfer
    Rindermann JJ, Akhtman Y, Richardson J, Brown T, Lagoudakis PG.
    J Am Chem Soc. 2010 Dec 14.
  2. Six-colour HyBeacon probes for multiplex genetic analysis
    Richardson JA, Gerowska M, Shelbourne M, French D, Brown T.
    Chembiochem. 2010 Dec 10;11(18):2530-3.
  3. Hybrid pore formation by directed insertion of α-haemolysin into solid-state nanopores
    Hall AR, Scott A, Rotem D, Mehta KK, Bayley H, Dekker C.
    Nat Nanotechnol. 2010 Dec;5(12):874-7.
  4. Quality control and single nucleotide resolution analysis of methylated DNA immunoprecipitation products
    Sengenès J, Daunay A, Charles MA, Tost J.
    Anal Biochem. 2010 Dec 1;407(1):141-3.
  5. Defining the limits of single-molecule FRET resolution in TIRF microscopy
    Holden SJ, Uphoff S, Hohlbein J, Yadin D, Le Reste L, Britton OJ, Kapanidis AN.
    Biophys J. 2010 Nov 3;99(9):3102-11.
  6. Sensing DNA opening in transcription using quenchable Förster resonance energy transfer
    Cordes T, Santoso Y, Tomescu AI, Gryte K, Hwang LC, Camará B, Wigneshweraraj S, Kapanidis AN.
    Biochemistry. 2010 Nov 2;49(43):9171-80.
  7. Identification of epigenetic DNA modifications with a protein nanopore
    Wallace EV, Stoddart D, Heron AJ, Mikhailova E, Maglia G, Donohoe TJ, Bayley H.
    Chem Commun (Camb). 2010 Nov 21;46(43):8195-7.
  8. Monitoring multiple distances within a single molecule using switchable FRET
    Uphoff S, Holden SJ, Le Reste L, Periz J, van de Linde S, Heilemann M, Kapanidis AN.
    Nat Methods. 2010 Oct;7(10):831-6.
  9. Single molecule analysis of combinatorial splicing
    Conze T, Göransson J, Razzaghian HR, Ericsson O, Oberg D, Akusjärvi G, Landegren U, Nilsson M.
    Nucleic Acids Res. 2010 Sep;38(16):e163.
  10. Nucleobase recognition in ssDNA at the central constriction of the alpha-hemolysin pore
    Stoddart D, Heron AJ, Klingelhoefer J, Mikhailova E, Maglia G, Bayley H.
    Nano Lett. 2010 Sep 8;10(9):3633-7.
  11. New strategy for the synthesis of chemically modified RNA constructs exemplified by hairpin and hammerhead ribozymes
    El-Sagheer AH, Brown T.
    Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15329-34.
  12. Nanoimprinted polymer chips for light induced local heating of liquids in micro- and nanochannels
    Thamdrup LH, Pedersen JN, Flyvbjerg H, Larsen NB, Kristensen A.
    Proc. SPIE 7764, 77640I (August 27, 2010)
  13. Fluorescence enhancement of single DNA molecules confined in Si/SiO2 nanochannels
    Westerlund F, Persson F, Kristensen A, Tegenfeldt JO.
    Lab Chip. 2010 Aug 21;10(16):2049-51.
  14. DNA translocation through graphene nanopores
    Schneider GF, Kowalczyk SW, Calado VE, Pandraud G, Zandbergen HW, Vandersypen LM, Dekker C.
    Nano Lett. 2010 Aug 11;10(8):3163-7.
  15. Surfing on a new wave of single-molecule fluorescence methods
    Hohlbein J, Gryte K, Heilemann M, Kapanidis AN.
    Phys Biol. 2010 Aug 4;7(3):031001.
  16. SNP discovery performance of two second-generation sequencing platforms in the NOD2 gene region
    Melum E, May S, Schilhabel MB, Thomsen I, Karlsen TH, Rosenstiel P, Schreiber S, Franke A.
    Hum Mutat. 2010 Jul;31(7):875-85.
  17. Characterizing single-molecule FRET dynamics with probability distribution analysis
    Santoso Y, Torella JP, Kapanidis AN.
    Chemphyschem. 2010 Jul 12;11(10):2209-19.
  18. Single-molecule denaturation mapping of DNA in nanofluidic channels
    Reisner W, Larsen NB, Silahtaroglu A, Kristensen A, Tommerup N, Tegenfeldt JO, Flyvbjerg H.
    Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13294-9.
  19. A flexible and fully integrated system for amplification, detection and genotyping of genomic DNA targets based on microfluidic oligonucleotide arrays
    Summerer D, Hevroni D, Jain A, Oldenburger O, Parker J, Caruso A, Stähler CF, Stähler PF, Beier M.
    N Biotechnol. 2010 May 31;27(2):149-55.
  20. Optimized localization analysis for single-molecule tracking and super-resolution microscopy
    Mortensen KI, Churchman LS, Spudich JA, Flyvbjerg H.
    Nat Methods. 2010 May;7(5):357-9.
  21. Urea facilitates the translocation of single-stranded DNA and RNA through the alpha-hemolysin nanopore
    Japrung D, Henricus M, Li Q, Maglia G, Bayley H.
    Biophys J. 2010 May 19;98(9):1856-63.
  22. In situ detection and genotyping of individual mRNA molecules
    Larsson C, Grundberg I, Söderberg O, Nilsson M.
    Nat Methods. 2010 May;7(5):395-7.
  23. Click chemistry with DNA
    El-Sagheer AH, Brown T.
    Chem Soc Rev. 2010 Apr;39(4):1388-405.
  24. Glycosylases and AP-cleaving enzymes as a general tool for probe-directed cleavage of ssDNA targets
    Howell WM, Grundberg I, Faryna M, Landegren U, Nilsson M.
    Nucleic Acids Res. 2010 Apr;38(7):e99.
  25. Light-Induced Local Heating for Thermophoretic Manipulation of DNA in Polymer Micro- and Nanochannels
    Thamdrup LH, Larsen NB, Kristensen A.
    Nano Lett. 2010 Mar 10;10(3):826-32.
  26. DNA in nanochannels - directly visualizing genomic information
    Persson F, Tegenfeldt JO.
    Chem Soc Rev. 2010 Mar;39(3):985-99.
  27. Single-molecule DNA biosensors for protein and ligand detection
    Lymperopoulos K, Crawford R, Torella JP, Heilemann M, Hwang LC, Holden SJ, Kapanidis AN.
    Angew Chem Int Ed Engl. 2010 Feb 8;49(7):1316-20.
  28. Conformational transitions in DNA polymerase I revealed by single-molecule FRET
    Santoso Y, Joyce CM, Potapova O, Le Reste L, Hohlbein J, Torella JP, Grindley ND, Kapanidis AN.
    Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):715-20.
  29. Multiple base-recognition sites in a biological nanopore: two heads are better than one
    Stoddart D, Maglia G, Mikhailova E, Heron AJ, Bayley H.
    Angew Chem Int Ed Engl. 2010;49(3):556-9.
  30. Detection of local protein structures along DNA using solid-state nanopores
    Kowalczyk SW, Hall AR, Dekker C.
    Nano Lett. 2010 Jan;10(1):324-8.
  31. Mass spectrometry tools for the classification and identification of bacteria
    Sauer S, Kliem M.
    Nat Rev Microbiol. 2010 Jan;8(1):74-82.