||List of Tasks in WP1
- 'MegaPlex PCR'
Targeted amplification using primers on a solid surface.
Targeted amplification in solution via DNA circularisation.
- 'Hybridisation Enrichment'
Benchmarking to evaluate pros, cons, efficiencies, and peculiarities of current methods.
- 'Rare Mutation Enrichment'
Recover rare somatic mutations from clinical DNA samples.
- 'Amplified Single-Molecule Arrays'
Creating sequencing substrates in situ via Selector driven DNA circularisation.
- 'Standardizing Data Output and Bioinformatic Strategies'
Define a standard data format for 2nd generation sequencers.
- 'Definition of ethical standards for info from 1st/2nd/3rd generation DNA analyzers'
With ethico-legal experts, analyse key issues and publish findings.